BiFET: sequencing Bias-free transcription factor Footprint Enrichment Test

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

DNaseI footprinting is an established assay for identifying transcription factor (TF)-DNA interactions with single base pair resolution. High-throughput DNase-seq assays have recently been used to detect in vivo DNase footprints across the genome. Multiple computational approaches have been developed to identify DNase-seq footprints as predictors of TF binding. However, recent studies have poin...

متن کامل

The Effect of Cognitive Bias Modification in the Attention Bias of Students With Test Anxiety

Abstract Introduction: Many of the students chr('39')educational problems, including academic failure and maladaptive behaviors, stem from exam anxiety caused by studentschr('39') cognitive bias. Cognitive bias modification can reduce attention biases students to be negative. Therefore, the purpose of the present study was to investigate the effectiveness of cognitive bias modification interven...

متن کامل

Bias in microRNA functional enrichment analysis

MOTIVATION Many studies have investigated the differential expression of microRNAs (miRNAs) in disease states and between different treatments, tissues and developmental stages. Given a list of perturbed miRNAs, it is common to predict the shared pathways on which they act. The standard test for functional enrichment typically yields dozens of significantly enriched functional categories, many ...

متن کامل

PCR-Activated Cell Sorting for Cultivation-Free Enrichment and Sequencing of Rare Microbes

Microbial systems often exhibit staggering diversity, making the study of rare, interesting species challenging. For example, metagenomic analyses of mixed-cell populations are often dominated by the sequences of the most abundant organisms, while those of rare microbes are detected only at low levels, if at all. To overcome this, selective cultivation or fluorescence-activated cell sorting (FA...

متن کامل

Microfluidic droplet enrichment for targeted sequencing

Targeted sequence enrichment enables better identification of genetic variation by providing increased sequencing coverage for genomic regions of interest. Here, we report the development of a new target enrichment technology that is highly differentiated from other approaches currently in use. Our method, MESA (Microfluidic droplet Enrichment for Sequence Analysis), isolates genomic DNA fragme...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2018

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/gky1117